NFL Week 2 Betting Model Picks and Predictions | 2025

Top 6 Record (Only Includes Week 1 So Far): 5 - 1 | Win Percentage: 83.3% | ROI: 59%

Overall Record (Only Includes Week 1 So Far): 10 - 5 - 1 | Win Percentage: 0% | ROI: 25.56%

Top 6 Picks:

• CAR +6.5

• DEN -1.5

• CLE +11.5

• TB +2.5

• BUF -6.5

• DAL -5

WAS vs GB | 9/11/25

WAS +3.4 | WAS @ GB

Confidence: 51.4%

The model likely favors WAS due to their moderate model confidence as a road underdog, potentially identifying favorable road performance metrics. Factors such as Washington's recent 3-2 ATS record and the opportunity for a competitive game against Green Bay could influence the model's confidence level. Additionally, the potential for coaching advantages or specific game situations that benefit Washington may contribute to the model's pick.

CLE vs BAL | 9/14/25

CLE +11.6 | CLE @ BAL

Confidence: 52.6%

The model likely identified that Cleveland's road performance metrics, combined with being a double-digit underdog, present value for them to cover against Baltimore. Despite Cleveland's recent struggles ATS, the model may see potential in their ability to keep the game closer than the spread suggests, especially when factoring in the historical head-to-head success Baltimore has had recently.

JAX vs CIN | 9/14/25

CIN -3.4 | CIN @ CIN

Confidence: 50.4%

The model likely favors CIN due to their recent strong ATS performance, going 4-1 in their last 5 games. Additionally, their 2-1 head-to-head record against JAX adds to the model's confidence in CIN covering as the home favorite. The data suggests that CIN's recent form and historical success against JAX are key factors in the model's pick.

NYG vs DAL | 9/14/25

DAL -5.3 | DAL @ DAL

Confidence: 51.8%

The model likely favors DAL due to their recent 4-1 ATS record, suggesting strong recent form and performance against the spread. Additionally, the historical head-to-head record (DAL 6-4 in last 10) may indicate a favorable matchup history for Dallas, contributing to the model's confidence in them covering -5.3, especially with the home field advantage factored in.

CHI vs DET | 9/14/25

CHI +6.0 | CHI @ DET

Confidence: 50.9%

The model likely favors CHI to cover due to the Bears' recent road performance and the matchup against DET. Factors like Chicago's defensive strength, Detroit's struggles, and the potential for a closely contested game could contribute to the model's confidence in the Bears staying within the +6.0 spread. The 50.9% confidence suggests a close call, emphasizing the importance of these key factors in the model's analysis.

NE vs MIA | 9/14/25

NE +1.0 | NE @ MIA

Confidence: 50.5%

The model likely favors NE to cover based on their recent road performance metrics, potential coaching advantages, and the opportunity as a road underdog. Despite recent ATS struggles, New England's ability to perform well on the road and possibly exploit specific matchups against Miami could have contributed to the model's confidence level. The moderate model confidence suggests that while there are factors in favor of New England covering, the outcome is still considered relatively uncertain.

SF vs NO | 9/14/25

NO +3.0 | NO @ NO

Confidence: 50.7%

The model likely favors NO due to their recent performance against the spread and historical success against SF. The home underdog status provides added value, while potential matchup advantages or situational factors such as offensive efficiency, defensive strengths, or coaching strategies may also contribute to the calculated edge. The 51% model confidence suggests a relatively balanced assessment, emphasizing the importance of these key factors in predicting a potential cover by NO.

BUF vs NYJ | 9/14/25

BUF -6.5 | BUF @ NYJ

Confidence: 51.9%

The model likely favors BUF due to their superior offensive metrics and the Jets' struggles defensively. Buffalo's strong road performance and coaching edge could also be contributing factors. Despite recent ATS trends and head-to-head history, the model suggests that the Bills have key advantages in this matchup that give them a slight edge to cover the spread.

SEA vs PIT | 9/14/25

SEA +3.0 | SEA @ PIT

Confidence: 51.1%

The model likely favors SEA's ability to perform as a road underdog based on historical data and situational factors. Factors such as favorable road performance metrics, potential undervaluation in the market due to recent poor ATS performance, and a well-coached team could contribute to the model's confidence in SEA covering the spread. Additionally, the model might see an opportunity for SEA to bounce back and exploit potential weaknesses in the PIT defense.

LA vs TEN | 9/14/25

TEN +5.5 | TEN @ TEN

Confidence: 51.0%

The model likely sees potential for TEN to cover based on factors such as the Titans being a home underdog, which historically holds value. Despite the recent ATS struggles, the model may believe that Tennessee's home-field advantage, along with factors like potential matchup advantages or game situations, could help them keep the game within the 5.5-point spread against the Rams.

CAR vs ARI | 9/14/25

CAR +6.5 | CAR @ ARI

Confidence: 54.9%

The models likely favor CAR due to their road performance metrics and the opportunity as a road underdog. Factors such as moderate model confidence, potential matchup advantages, recent form, and possibly undervaluing by the market could contribute to the calculated edge in picking CAR +6.5. Additionally, the historical head-to-head trend of ARI going 2-2 in the last four games may also play a role in the model's confidence level for this pick.

DEN vs IND | 9/14/25

DEN -1.5 | DEN @ IND

Confidence: 53.9%

The model likely favors DEN to cover due to their moderate model confidence combined with being a road favorite. Factors such as Denver's road performance metrics, potential offensive/defensive matchups, and coaching advantages may have contributed to the model's preference for DEN in this game. The recent form of Denver going 3-2 ATS in their last 5 games and the head-to-head history being split 1-1 between the two teams may have also influenced the model's confidence level.

PHI vs KC | 9/14/25

KC +0.9 | KC @ KC

Confidence: 51.0%

The model likely identified matchup advantages for KC in this game, such as their strong offense against Philadelphia's struggling defense. Home field advantage and the potential for a bounce-back performance from KC could also be factors contributing to the model's confidence. Additionally, recent trends like KC's 3-2 ATS record in the last 5 games might suggest a positive outlook for them in this matchup.

ATL vs MIN | 9/14/25

MIN -3.5 | MIN @ MIN

Confidence: 51.3%

The model likely favors MIN to cover due to their recent 4-1 ATS record, suggesting strong recent form. Home field advantage could also play a role in the pick, as well as potential matchup advantages for MIN against ATL's defense. The moderate confidence level may stem from MIN's consistency and positive trends compared to ATL's recent struggles.

TB vs HOU | 9/15/25

TB +2.4 | TB @ HOU

Confidence: 52.0%

The model likely favors TB due to their recent ATS performance and the fact that they are the road underdog. TB's ability to cover on the road could be a key factor, along with potential weaknesses in HOU's defense that TB's offense could exploit. The moderate model confidence suggests a balanced assessment of various factors, with TB having a chance to outperform expectations in this matchup.

LAC vs LV | 9/15/25

LV +3.4 | LV @ LV

Confidence: 51.4%

The model likely favors LV to cover based on their recent ATS performance (4-1 in last 5) and historical head-to-head success against LAC (7-3 in last 10). Additionally, being a home underdog adds value as LV might benefit from home field advantage and potentially exploit matchup advantages against LAC. The moderate model confidence suggests that while there are factors favoring LV, the game remains relatively close and could swing either way.